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Oxidative stress
Oxidative stress
Oxygen is vital because it allows the production of energy from organic matter. Paradoxically, oxygen can also be harmful: physiological processes such as cellular respiration or protective mechanisms of the body constantly produce highly reactive oxygen compounds, including free radicals, all highly toxic.
Oxidative stress is defined as a disturbance in the balance between the production of free radicals and the ability of the body to neutralize them leading to an accumulation of free radicals. Oxidative stress over a long period may promote the development of diseases: cardiovascular diseases, chronic infectious diseases, inflammatory and neurodegenerative diseases and even cancer. Besides, oxidative stress plays also an important role in aging.
The factors or conditions below may contribute to oxidative stress:
- Heavy physical efforts
- Unbalanced diet
- Consumption of tobacco and alcohol
- Chronic fatigue
- Physical or mental stress
- Chronic and inflammatory diseases
- Treatments such as chemotherapy, radiotherapy, oral contraception
- Pollution, UV radiation
- Infections
There is a conclusive link between high levels of oxidative stress and a patient’s health.
However, in more than 80% of cases, it is possible to reduce oxidative stress and thus to improve health status, regardless of clinical context or patient’s age.
Targeted laboratory diagnoses are therefore essential for an early diagnosis and treatment of oxidative stress.
Laboratoires Réunis offers, in addition to a wide range of individual analyses, the following laboratory diagnostic profiles for the detection of oxidative stress:
- Oxidative stress-base profile: antioxidative capacity, oxidized LDL and 8-OHdG
- Profile of complete oxidative stress: antioxidant capacity, 8-OHdG, oxidized LDL, SOD, GPX, Se, Zn, Vit A & E, ubiquinone, citrulline, nitrotyrosine,
- Nitrosative stress profile: ubiquinone, nitrotyrosine, nitrophenylacetic acid, citrulline